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Importantly, reduced food intake during GLP-1RA therapy may arise from overlapping but non-equivalent mechanisms, including homeostatic suppression, interoceptive-state-dependent revaluation, and reward-related downregulation of food cue value
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95 Most recently, the REWIND trial comparing dulaglutide (1.5 mg weekly) to placebo demonstrated reduced combined MACE with dulaglutide treatment (12.0% vs 13.4%, HR 0.88, 95% CI 0.79-0.99
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